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"When the day comes that we get married, the most important person to us will not be there, but don't worry, he'll be up there watching, hopefully with a big smile on his face. We love you Charlie and your legacy will carry on"

The parents, who are aged in their 30s, have launched a foundation to provide a "brighter future" for other sick children.

The couple, from Bedfont, west London, raised more than £1.3m to pay for therapy in America and said they wanted to establish a foundation with the donations.

They also said they want to raise awareness of mitochondrial depletion syndrome.

"Our vision is to enhance the quality of life for mitochondrial sufferers through innovative research, family support, and raise much-needed awareness for this devastating condition," they said on the Charlie Gard Foundation website.

Doctors at Great Ormond Street Hospital for Children in London said the therapy would not help and said life-support treatment should stop.

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Diets that sound too good to be true are often just that. But a plan called intermittent fasting that frees its followers from calorie counting and carb cutting is quickly gaining traction in Silicon Valley. Scientific research suggests its followers are onto something big.

Popularized by Bay Area health nuts who don't mind being guinea pigs for science, intermittent fasting (or simply "IF" among fans), involves limiting the time you eat to a specific time period each day. While most of us snack somewhat regularly from the time we wake up until the time we go to sleep, intermittent fasters only "feed" within a strictly defined window, often from morning to afternoon or afternoon to evening.

Silicon Valley loves it. One Bay Area group of enthusiasts called WeFast meets weekly to collectively break their fasts with a hearty morning meal. Facebook executive Dan Zigmond confines his eating to the narrow time slot of 9 a.m. to 5:30 p.m., and many other CEOs and tech pioneers are sworn "IF" devotees.

Despite not requiring followers to count calories, ban carbs, or restrict their eating to celery and juice, intermittent fasting has been shown to be just as helpful for weight loss as traditional diets. And animal studies hint that the plan could have a range of other health benefits from curbing cancer risk to even prolonging life.

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