Baumhefner said for many patients with breakthrough disease on standard IFNβ-1a, increasing the treatment dosage with twice-weekly therapy may be an acceptable alternative to switching treatments.
June Halper, MSN, MSCN, CMCS CEO, agreed, noting that "it makes a lot of sense for some patients to stay on a drug that has worked for them, and tweak the therapy if there is a breakthrough instead of automatically moving on to another drug," she told MedPage Today.
Baumhefner said a prospective, blinded, randomized trial comparing once-weekly and twice-weekly intramuscular IFNβ-1a may be warranted..
For treatment to be successful, up to 12 vials of anti-venom must be administered in quick succession.
“She was unconscious and everyone thought she would die but I administered diluted hydrocortisone and adrenalin shots through her thighs and arm. After some time she woke up and sat down, I knew she would survive,” Musyoka said.
“Were it not for him, I would be dead because after the bite, I was rushed to Mathuki Health Centre but there was no doctor in sight. He saved my life,” said Joshua.
With the recent listing of snakebites among the Neglected Tropical Diseases, it is expected that the serious public health concern in sub- Saharan Africa will receive the required attention and funding for accessible and affordable anti-venom following the unanimous resolutions of several nations at World Health Assembly in Geneva. .