PLOS Pathogens publishes Open Access research and commentary that significantly advance the understanding of pathogens and how they interact with host organisms.
C. difficile infections kill 29,000 Americans a year and make 450,000 sick in the U.S. alone, according to the Centers for Disease Control and Prevention.
It causes unremitting diarrhea, which can weaken patients being treated for pneumonia, cancer and other illnesses.
Right now, antibiotics can make patients even sicker because they kill not only the C. difficile, but so-called good bacteria that keep things in balance. Once other bacteria are killed off, C. diff, as it’s commonly known, can come back and even proliferate — without competition.
Poop transplants aim to restore the balance with healthy bacteria.