In West Bengal, one more patient with mysterious fever, suspected to be infected by Nipah virus, was on Tuesday ( May 29) admitted to ID Hospital in Beliaghata here. Further, samples sent from cattle and pigs in the vicinity that were also sent tested negative for Nipah virus. This was the first NiV outbreak in South India. Doctors suspect the virus had spread from a 26-year-old, triggering an outbreak in Kozhikode.
According to the WHO report, 600 Nipah cases were reported in the world from 1998 to 2015.
"We had taken him to Domkol hospital, then to Baharampur and finally here after consultation with the medics there", they said. A multi-disciplinary team led by the Indian Government's National Centre for Disease Control (NCDC) is in Kerala in response to the outbreak.
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Symptoms of the infection include fever, headache, drowsiness, respiratory illness, disorientation and mental confusion, and patients progress into a coma within 24-48 hours.
The good thing is the government of India has capacity to deal with Nipah.
However, the disease itself was contained quickly before it could become an outbreak.
"Most of the devastating infectious diseases in human history began as infections that spilled over from animals and people and then acquired the capacity for efficient person-to-person transmission", he explained. And despite there being an abundance of the type of bat that carries Nipah, the body of evidence suggests that the virus is rarely found even in these bats..
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Citation: Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLoS Pathog 14(5): e1007065. https://doi.org/10.1371/journal.ppat.1007065
Editor: Margaret A. Phillips, U Tex SouthWestern, UNITED STATES
Received: November 6, 2017; Accepted: April 30, 2018; Published: May 31, 2018
Copyright: © 2018 Wen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the paper and its Supporting Information files.
Funding: This work was supported in part by the National Institutes of Health, National Institute of Allergy and Infectious Diseases grants (R01AI054578; R01AI136031) to NJG and National Institute of General Medical Sciences grant (R01GM11059) to YWY. A mini-center pilot grant (to NJG) and data acquisition award (to JJW) from the Institute for Human Infections and Immunity, UTMB, Galveston also supported part of the presented studies. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.